Welcome to the Brain Mind Institute

The mission of the Brain Mind Institute is to understand the fundamental principles of brain function in health and disease, by using and developing unique experimental, theoretical, technological and computational approaches. The scientific challenge addressed by the BMI consists in connecting different levels of analysis of brain activity, such that cognitive functions can be understood as a manifestation of specific brain processes; specific brain processes as emerging from the collective activity of thousands of cells and synapses; synaptic and neuronal activity in turn as emerging properties of the biophysical and molecular mechanisms of cellular compartments. Understanding information processing in the brain and its higher emerging properties is arguably one of the major challenges in the life sciences. Research at the BMI focuses on three main areas: i)Molecular neurobiology and mechanisms of neurodegeneration; ii)Molecular and cellular mechanisms of synapse and microcircuit function up to the behavioural level and including metabolic aspects; iii) Sensory perception and cognition in humans. In all areas, the BMI strives to integrate knowledge gained by multidisciplinary approaches and across different disciplines and research laboratories.

Finally, underlying all levels of analysis, research at BMI is characterized by a sustained interest in pathological processes. In order to achieve these scientific goals, the Brain Mind Institute benefits from a unique academic environment:

	*	An institute organized as a network of independent laboratories reflecting complementary technological approaches; each laboratory collaborates with several others within the institute in addition to cross-disciplinary interactions on campus.
	*	A campus that stands out as a premier technological university in engineering, computer science and basic sciences.
	*	An intimate collaboration with the Blue Brain Project which stands out as one of the most challenging neuroscience simulation and databasing projects worldwide.
	*	A proximity to and joint affiliations of our faculty with top university hospitals in Lausanne and Geneva in particular for projects related to cognition and neurodegenerative diseases.
	*	A new initiative in neuroprosthetics to which the BMI is strongly committed that will further the collaboration with engineering sciences by a host of inspiring common projects.

BMI's groups have access to a state-of-the-art imaging center, the Center for Biomedical Imaging (CIBM), created through a joint effort of EPFL, Geneva University (UNIGE) and Hospital (HUG), Lausanne University (UNIL) and Hospital (CHUV) and the Leenaards and Jeantet Foundations. The Center, distributed between HUG, CHUV and EPFL, includes high-end MR, PET, EEG and signal processing equipment. (Link to CIBM)

A feature of the Brain Mind Institute is that several faculty members have strong expertise in physics or mathematics; this holds not only for theoretical but also for experimental neuroscience. In this way the Brain Mind Institute reflects the mission of the School of Life Science: to provide a life science curriculum with a strong emphasis on quantitative approaches. As far as teaching is concerned, the BMI Faculty is committed to provide a comprehensive and formal training in neuroscience from the undergraduate to the graduate levels.

Latest News

	Stress at learning facilitates memory formation / NOV. 2009 Although stress is frequently regarded as deleterious for cognition, there are many instances in which a certain stress level can facilitate learning and memory. Dr. Lisa Conboy and Prof. Carmen Sandi (LGC-Laboratory of Behavioral Genetics) have underscored key molecular mechanisms related to the synaptic trafficking of glutamate receptors whereby stress experienced at learning facilitates memory formation. More >>>
	how good are neuron models / oct. 2009 Wulfram Gerstner and Richard Naud have published an article in the magazine Science. Abstract excerpt: Opinions strongly diverge on what constitutes a good model of a neuron (1-3). Two lines of thought on this have coexisted for a long time: detailed biophysical models (of the style proposed in 1952 by the physiologists Alan Hodgkin and Andrew Huxley) that describe ion channels on the tree-like spatial structure of the neuronal cell (4), and simple "integrate-and-fire" models based on the much older insight that pulsatile electrical activity (known as an action potential or spike) is a threshold process. (...) More >>>
	Pierre Magistretti elected Ibro secretary-general, 2010-2013 / oct. 2009 Prof. Pierre Magistretti has been endorsed by IBRO's Governing Council as the next Secretary-General of IBRO. His three-year term of office begins in January 2010. Until he takes up office, Prof. Pierre Magistretti will be Secretary-General-Elect, working closely with current Secretary-General of IBRO, Prof. Marina Bentivoglio. More >>>

Upcoming Seminars

BMI Seminars

Lausanne Neuroscience Seminar